Bioequivalence Evaluation of Two Atenolol Tablet Preparations in Korean Healthy Male Volunteers

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Comparative pharmacokinetics and bioequivalence of two 50 mg atenolol tablet formulations in healthy Korean male volunteers.

Atenolol is a selective β1 receptor antagonist that is available as a racemic mixture. The objective of this study was to compare the pharmacokinetics and evaluate the bioequivalence of 50 mg atenolol test and reference formulations in 24 healthy Korean male volunteers.This study was a single-dose, randomized, open-label, 2 period crossover study. 24 healthy Korean male volunteers randomly rece...

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Comparative Pharmacokinetics and Bioequivalence of Two 50 mg Atenolol Tablet Formulations in Healthy Korean Male Volunteers

▼ Atenolol is a selective β 1 receptor antagonist that is available as a racemic mixture. The objective of this study was to compare the pharmacokinetics and evaluate the bioequivalence of 50 mg atenolol test and reference formulations in 24 healthy Korean male volunteers. This study was a single-dose, randomized, openlabel, 2 period crossover study. 24 healthy Korean male volunteers randomly r...

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Comparative Pharmacokinetics and Bioequivalence of Two 50 mg Atenolol Tablet Formulations in Healthy Korean Male Volunteers

▼ Atenolol is a selective β 1 receptor antagonist that is available as a racemic mixture. The objective of this study was to compare the pharmacokinetics and evaluate the bioequivalence of 50 mg atenolol test and reference formulations in 24 healthy Korean male volunteers. This study was a single-dose, randomized, openlabel, 2 period crossover study. 24 healthy Korean male volunteers randomly r...

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Bioequivalence Studies of Two Formulations of Baclofen Tablet in Healthy Volunteers

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Bioequivalence Studies of Two Formulations of Baclofen Tablet in Healthy Volunteers

The relative bioavailability of the test (generic) product 2 × 25 mg baclofen tablets, with respect to the reference product, Lioresal® 2 × 25 mg tablets (baclofen; Squibb) was determined in a single-blind, single dose, randomised, crossover study. The mean values for the variable Cmax were 737.6 ng/ml for the reference and 739.5 ng/ml for the test product. The mean values for the variable AUC ...

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ژورنال

عنوان ژورنال: Biomolecules and Therapeutics

سال: 2007

ISSN: 1976-9148

DOI: 10.4062/biomolther.2007.15.3.187